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Early stage alterations in CA1 extracellular region proteins indicate dysregulation of IL6 and iron homeostasis in the 5XFAD Alzheimer's disease mouse model
Gürel, Büşra; Cansev, Mehmet; Sevinç, Cansu; Keleştemur, Seda; Öcalan, Büşra; Çakır, Ayşen; Aydın, Sami; Kahveci, Nevzat; Ozansoy, Mehmet; Taşkapılıoğlu, Özlem; Ulus, İsmail Hakkı; Karayel Başar, Merve; Şahin, Betül; Tüzüner, Mete Bora; Baykal, Ahmet Tarık (Ios Press, 2018)In recent years, an increasing number of research papers revealed that the compositional and volumetric alterations in the extracellular matrix are the consequences of aging and may be related to Alzheimer's disease (AD). ... -
Proteomics analysis of CA1 region of the hippocampus in pre-, progression and pathological stages in a mouse model of the alzheimer’s disease
Gürel, Büşra; Cansev, Mehmet; Koç, Cansu; Öcalan, Büşra; Çakır, Aysen; Aydın, Sami; Kahveci, Nevzat; Ulus, İsmail Hakkı; Şahin, Betül; Başar, Merve Karayel; Baykal, Ahmet Tarık (Bentham Science Publishers, 2019)Background: CA1 subregion of the hippocampal formation is one of the primarily affected structures in AD, yet not much is known about proteome alterations in the extracellular milieu of this region. Objective: In this ...